International Customers

上野医院 Ueno Clinic

Nagano City · Est. Meiji 43 · 30 Years of Care

Advanced Beauty
in Nagano 5 min from Zenkoji Temple

Visiting Zenkoji Temple, Snow Monkey Park, Hakuba, or Togakushi? Add a moment of renewal to your journey at Nagano’s trusted aesthetic clinic.

PRP Regenerative Therapy Stem Cell Supernatant PicoSure Laser Placenta Injection HEALITE LED Medical Hair Removal

↓ Explore

Four Ways to
Renew in Nagano

Each treatment is selected for its clinical evidence, safety profile, and unique availability in Japan.

Everything in
One Visit.

IV drips can be administered simultaneously with Healite II therapy. Add a Foot Massage to any treatment for complete head-to-toe care — ideal for travelers.

IV + Healite II Simultaneously

Receive your Glutathione or Vitamin C drip while Healite II works on your chosen area(s) — face, neck, back, knees, calves or feet. No extra time needed.

点滴施術中に同時にヒーライト照射が可能。時間を無駄にしません。
点滴期间同时进行光线疗法,一举两得。
IV Drip Therapy — Vitamin C / Glutathione
Foot Massage at Ueno Clinic — relax & recover

Add a Foot Massage (non-LED)

Standalone Foot Massage is ¥11,000. Combine with any IV drip or Healite II session and it becomes ¥8,800 — perfect for recovering from a day of sightseeing in Nagano.

フットマッサージ単独¥11,000 / 点滴・ヒーライトとセット¥8,800。長野観光の疲れをリセット。
足部按摩单独¥11,000,与点滴或光疗组合¥8,800。
Healite II + Foot Massage
ヒーライト+フットマッサージ
¥23,100 ¥19,800
Save ¥3,300
Glutathione + Healite II
グルタチオン+ヒーライト · 谷胱甘肽+光疗
¥28,600 ¥25,300
Save ¥3,300
Vitamin C + Healite II
ビタミンC+ヒーライト · 维C+光疗
¥25,300 ¥22,000
Save ¥3,300
Glutathione + Vitamin C
グルタチオン+ビタミンC · 谷胱甘肽+维C
¥30,800 ¥27,500
Save ¥3,300
Glutathione + Vitamin C + Healite II — Best Value
全部のせセット · 全套组合 · グルタチオン+ビタミンC+ヒーライト
¥39,600 ¥36,300
Save ¥3,300

All prices tax included 全て税込 · Prices shown are Guesthouse OKAERI guest prices · Regular prices are ¥2,200–¥3,300 higher

Treatment 01

Healite II LED Therapy

光线疗法 — 顔面 + フットケア

“Glow & Recover. No needles. No downtime.”

Healite II LED Light Therapy

What is Healite II?

Healite II is an FDA-cleared LED phototherapy device by Lutronic, delivering specific wavelengths — 633nm red light for collagen stimulation and anti-ageing, and 830nm near-infrared for deep tissue healing and anti-inflammation. Pain-free, non-invasive photobiomodulation.

Healite II can be applied to multiple body areas, not just the face — neck & décolletage, shoulders & back, arms, knees, calves and feet. Choose one or several areas based on your concern. A separate Foot Massage service (non-LED) is also available, ideal for travel-tired legs.

光线疗法 — 中文简介 光疗利用红光与近红外线刺激细胞内线粒体,促进胶原蛋白生成、改善暗沉与肌肤弹力。可照射于面部、颈部、肩背、手臂、膝盖、小腿、脚部等部位。无创、无恢复期。可同时进行点滴施术。
  • Supports collagen & elastin production
  • Improves skin tone, texture & luminosity
  • Reduces post-flight puffiness & dullness
  • Soothes shoulders, back, knees, calves & tired feet
  • Combinable with IV drips in same session
  • Zero downtime — return to sightseeing immediately

Pricing (税込)

Healite II — Multi-area pricing
1 area (e.g. face)¥11,000
2 areas (+¥8,800)¥19,800
3 areas (+¥6,600)¥26,400
Areas: face · neck/décolletage · shoulders/back · arms · knees · calves · feet
Foot Massage (separate service · non-LED)
Standalone¥11,000
Add-on (with IV or Healite II)¥8,800
IV Combos
Glutathione + Healite II¥25,300
Vitamin C + Healite II¥22,000
★ Guesthouse OKAERIご滞在のお客様価格です。通常価格は¥2,200–¥3,300高くなります。

Book Healite II → Healite II — application to neck, shoulders, back, arms, knees, calves & feet
Treatment 02

Glutathione IV

谷胱甘肽点滴 — 抗氧化・排毒・透明感

“Your body’s master antioxidant — amplified.”

What is Glutathione IV?

Glutathione is the most potent antioxidant naturally produced by the human body. IV administration bypasses digestive breakdown, delivering pharmacological concentrations directly into the bloodstream.

谷胱甘肽点滴 — 中文简介 谷胱甘肽是人体内最强的抗氧化物质。静脉注射可直接进入血液循环,帮助清除自由基、促进肝脏排毒、改善肌肤暗沉。可与光线疗法同时进行,一次就诊双重护理。
  • Deep detoxification & liver support
  • Free radical elimination
  • Improved skin luminosity & even tone
  • Antioxidant & immune support
  • Can be combined with Vitamin C IV
  • Simultaneous with Healite II therapy
⚠ Important Notice Offered for antioxidant and detoxification purposes. Effects vary individually. Physician consultation required.
Glutathione IV Drip Therapy

Pricing (税込)

Single
Glutathione IV¥16,500
Sets
Glutathione + Healite II¥25,300
Glutathione + Vitamin C¥27,500
Gluta + Vitamin C + Healite II¥36,300
★ Guesthouse OKAERIご滞在のお客様価格です。

Book Glutathione →
Treatment 03

High-Dose Vitamin C IV

“Build collagen. Boost immunity. Glow from within.”

Why IV, Not Oral?

Oral Vitamin C absorption is capped by the intestine. Intravenous delivery achieves pharmacological plasma concentrations — unlocking effects not possible with supplements. Backed by a 2025 review analyzing 150+ clinical studies.

  • Cofactor for collagen & elastin synthesis
  • Enhances immune cell activity
  • Powerful antioxidant at pharmacological doses
  • Reduces fatigue & supports recovery
  • Synergistic with Glutathione IV
  • Simultaneous with Healite II therapy
⚠ Screening Note Patients with G6PD deficiency should not receive high-dose Vitamin C IV. Kidney conditions should be disclosed. Physician consultation required.
Vitamin C IV Drip Therapy

Pricing (税込)

Single
Vitamin C IV (12.5g)¥13,200
Sets
Vitamin C + Healite II¥22,000
Glutathione + Vitamin C¥27,500
Gluta + Vitamin C + Healite II¥36,300
★ Guesthouse OKAERIご滞在のお客様価格です。

Book Vitamin C IV →
Treatment 04 · 限定日本

胎盘素注射

Placenta Injection — 厚生劳动省认可药品

全球唯一,只有日本才能体验的正规人胎盘素注射。

为什么只有日本有?

日本厚生劳动省认可的人胎盘素注射剂,全球仅有两种:Laennec(ラエンネック)Melsmon(メルスモン)。这两种药品仅在日本制造、销售。

胎盘素有效成分 氨基酸 · 维生素 · 矿物质 · 核酸 · 细胞生长因子。促进细胞再生与代谢,50年以上临床实绩,零感染报告。
  • 促进细胞再生与活化
  • 改善肌肤暗沉、细纹与弹力
  • 调节荷尔蒙平衡(更年期症状改善)
  • 改善肝功能(Laennec 保险适应症)
  • 疲劳恢复与全身细胞活化
⚠ 重要说明 / Important 注射胎盘素后,将终身无法献血(日本厚生劳动省规定)。请确认您已了解此事项。
Placenta Injection Therapy

Pricing (税込)

料金 / Price
Placenta Injection (1 amp)¥6,600
★ Guesthouse OKAERIご滞在のお客様価格です。通常価格¥8,800。
预约时请告知「Guesthouse OKAERIから」。

立即预约 / Book Now →

Book Your Treatment

📅 Appointment Days
Friday & Saturday Only
Fri 9:00–20:00  ·  Sat 9:00–15:00
仅限周五・周六 · 金・土曜日のみ

We confirm within 24 hours by email.
填写以下表格,24小时内邮件确认。Guesthouse OKAERIご宿泊の方は必ずその旨をご記入ください。

Personal Information
Guesthouse — ゲストハウス
Treatment Selection
Medical Intake / 问诊

🌏 International Guests: Fri 9:00–20:00 · Sat 9:00–15:00 · By appointment only · Email only — no English phone support  |  🇯🇵 日本語サイトはこちら

⭐ Recommended: PRP for skin regeneration · HEALITE or Placenta Injection for travel fatigue recovery · Acupuncture & Osteopathy for tired shoulders & back (same facility)

Ueno Clinic has served the Nagano community for over 30 years, offering advanced cosmetic treatments in a private, unhurried setting. Whether you’re here for Zenkoji Temple, Snow Monkey Park, Hakuba Valley, or Togakushi Shrine — add a moment of renewal to your journey.

From Zenkoji Temple, a taxi takes less than 5 minutes and costs under ¥1,000.

Guests have visited from
🇹🇼 Taiwan
🇨🇳 China
🇰🇷 Korea
🇹🇭 Thailand
🕐
International Hours
Friday 9:00 – 20:00
Saturday 9:00 – 15:00
📵 Phone: English not available
💬 Email only
Please contact us at least 1 day in advance
📋
Before Your Treatment
We provide a full explanation in English before every treatment — including procedure details, what to expect, risks, aftercare, and pricing.

No surprises. No language barriers. Your comfort and understanding come first.
Recommended for Visitors
PRP — Premium skin regeneration
HEALITE — Relax & recover from travel
Placenta Injection — Fatigue recovery
Acupuncture & Osteopathy
Same facility · Tired shoulders, back & body

What We Offer

All treatments are performed by our licensed physicians. Results may vary by individual.

01 PRP SKIN REGENERATIVE THERAPY
PRP skin regeneration — natural radiance
Ueno Clinic · Nagano City
PRP Skin
Regeneration Therapy

Anti-aging skin care that activates your body’s own healing power — for lasting, natural rejuvenation

Harnesses your body’s natural regenerative ability — no foreign substances
Government-registered regenerative medicine facility (since 2007)
Highly sustainable results with long-lasting skin improvement
100% Natural PRP · Zero Additives · Zero Impurities
01
PRP Skin Regenerative Therapy
Govt-Registered Facility Since 2007 · 17+ Years Zero Additives Your Own Blood

“I’ve been noticing dullness and loss of firmness lately” — PRP therapy is one of our most requested treatments at Ueno Clinic.

PRP (Platelet-Rich Plasma) uses growth factors concentrated from your own blood to stimulate skin regeneration from within. Because it uses your own blood, the risk of allergic reaction is extremely low.

The blood is drawn, centrifuged to extract the platelet-rich layer, and then reintroduced into the skin — encouraging your body’s own regenerative processes naturally and safely. The treatment itself takes approximately 30 minutes on the day of your visit. (Initial consultation and counselling require additional time on your first visit.)

Science
How PRP Skin Regeneration Works
① Aging Skin
Collagen depleted · Elasticity reduced
② PRP Injected
Concentrated platelets introduced
③ Cells Activated
Growth factors released · Fibroblasts activated
④ Skin Renewed
Collagen synthesised · Radiance restored
Three Stages of Action
1
Collected blood is centrifuged to significantly increase platelet concentration, isolating the platelet-rich plasma (PRP) layer.
2
PRP is precisely injected into the target skin layer. Platelets begin releasing growth factor proteins immediately upon contact with tissue.
3
Activated skin cells undergo division and regeneration — stimulating natural collagen and hyaluronic acid synthesis from within the dermis.
Active Growth Factors in PRP
TGF-β (Transforming Growth Factor)
Epithelial cell growth, vascular proliferation, wound repair
PDGF (Platelet-Derived Growth Factor)
Cell proliferation, collagen synthesis, angiogenesis
VEGF (Vascular Endothelial Growth Factor)
Vascular endothelial proliferation, tissue nourishment
EGF (Epidermal Growth Factor)
Epithelial cell proliferation, tissue repair and regeneration

We use different PRP protocols tailored to each individual’s skin condition and treatment goals.

Procedure
Step-by-Step Treatment Protocol
💉
1
Preparation
  • Anticoagulant solution drawn into syringe
  • Air expelled, butterfly needle attached
  • Equipment checked before draw
🩸
2
Blood Collection
  • Up to 15 ml collected slowly
  • Gently mixed with anticoagulant
  • Volume tailored to individual
🔬
3
Transfer & Tube
  • Blood transferred to YCELL tube
  • Precise angle for clean transfer
  • Single controlled pour
⚗️
4
Centrifugation
  • Tubes sealed and balanced
  • First spin: 3,400 rpm
  • Second spin per protocol
🧪
5
Extraction Prep
  • Buffy coat raised to extraction zone
  • Caps disinfected with alcohol swab
  • Stoppers removed for extraction
6
PRP Extraction
  • PRP layer collected via syringe
  • Pure PRP, free of red blood cells
  • Ready for injection
Injection Method: PRP is administered using a technique personalised to your skin concerns — options include macro-cannula, water-light injection, and MESOGUN micro-injection. Your physician will recommend the most suitable method at your consultation.

Ueno Clinic has been offering PRP since 2007 and is a facility registered under Japan’s Act on the Safety of Regenerative Medicine — a status held by only a limited number of clinics nationwide. Our PRP contains zero additives, keeping the treatment as close to natural as possible.

Recommended for: skin texture, fine lines, under-eye concerns, enlarged pores, overall radiance and firmness.

1st session: ¥203,500 (tax incl.)
2nd session onwards: ¥101,750

Full details (Japanese) →
02 STEM CELL SUPERNATANT
01 PRP Skin Regenerative Therapy
02
Umbilical Cord Stem Cell Supernatant
Japan-Made Umbilical Cord Origin GDF-11 Youth Factor No Downtime No Rejection Risk
Stem cell culture supernatant skin treatment — Ueno Clinic Nagano

Stem Cell Supernatant · Japanese-made · ¥44,000 (face)

The next generation of skin regeneration — harnessing the power of over 500 growth factors to renew skin at a cellular level.

Stem cell culture supernatant is the liquid medium remaining after stem cells are cultivated. During the growth process, stem cells release over 500 types of cytokines, growth factors, and exosomes into this liquid — giving it remarkable regenerative and reparative properties.

Unlike PRP (which uses your own blood), the supernatant is injected subcutaneously into the face, where it works directly on the skin’s deeper layers to stimulate collagen synthesis, improve texture, and restore vitality.

Ueno Clinic uses Japanese-made supernatant — selected for its quality control, safety standards, and high concentration of active factors. This distinguishes it from lower-quality imported alternatives.

No downtime. Can be combined with PRP or HEALITE for enhanced results.

How It Works
🔬
GDF-11 & Cytokines
Harvard-researched GDF-11 “youth factor” + hundreds of cytokines stimulate cell repair and tissue regeneration
💫
Collagen Synthesis
Activates fibroblasts to produce new collagen and elastin — improving firmness and reducing fine lines
🌿
Anti-Inflammation
Exosomes reduce inflammation, support skin barrier function, and improve overall skin conditioning
🇯🇵
🇯🇵 Domestic · Umbilical Cord Origin · Strictly Screened
Sourced from Japanese donors at approved domestic medical facilities. Passes 5 virus screenings (HBV, HCV, HIV, HTLV-1, B19V) and 4 bacterial tests. Stored at −80°C ultra-low temperature freezer to maintain full potency. Used immediately after thawing for maximum freshness and efficacy.

Recommended if you —

  • Want next-level skin regeneration beyond what PRP alone provides
  • Are concerned about skin texture, fine lines, dullness, or loss of firmness
  • Have acne scarring or uneven skin tone
  • Prefer a treatment using no animal-derived or foreign substances
  • Want to combine with PRP for a powerful synergistic effect
  • Are seeking the latest in Japanese regenerative aesthetics
Face (subcutaneous injection): ¥44,000 (tax incl.)

Enquire via Email →
03 PICOSURE LASER
03
PicoSure Laser
US FDA Cleared No Downtime Same-Day Makeup Limited Facilities in Nagano
PicoSure picosecond laser device — Ueno Clinic Nagano

PicoSure® by Cynosure, USA · World’s first picosecond laser

PicoSure is the world’s first picosecond-pulse laser, developed by Cynosure (USA) and cleared by the US FDA — the equivalent of Japan’s Ministry of Health, Labour and Welfare approval. It fires laser energy in trillionths of a second, shattering melanin pigment particles with precision while minimising thermal damage to surrounding tissue.

Unlike conventional lasers, PicoSure requires no protective tape or crust period after treatment. Makeup can be applied on the same day, making it an ideal choice for travellers who cannot afford downtime.

Clinics offering PicoSure in Nagano City are very limited. Ueno Clinic has been one of the few facilities in the area equipped with this device since its introduction in 2017.

Recommended if you —

  • Have visible age spots, freckles or sun damage you’d like to reduce
  • Want to improve melasma, dullness, or uneven skin tone
  • Are bothered by enlarged pores or fine lines
  • Have acne scars (pigmentation or surface texture)
  • Have tried conventional laser elsewhere without satisfactory results
  • Want to avoid post-treatment protective tape or downtime
  • Are considering tattoo or art makeup removal
Trial spot (1 cm²): ¥6,600
Single spot (1 cm²): ¥16,500
Full face — light spots / dullness: ¥27,500
Full face — pores / texture / acne scars: ¥38,500
Full face — deeper pigmentation: ¥38,500

Full details (Japanese) →
04 PLACENTA INJECTION
04
Placenta Injection
Travel-Friendly Quick Treatment No Downtime

Fatigue, skin concerns, and menopausal symptoms — Placenta therapy works from within to restore balance and vitality.

Placenta extract (derived from human placenta) is rich in amino acids, vitamins, minerals, and bioactive growth factors. Based on years of clinical research, it has long been used in Japan for fatigue recovery, skin rejuvenation, and anti-ageing support.

The injection takes only a few minutes with minimal discomfort and no downtime — making it an ideal treatment to fit around a busy travel itinerary. Many international guests choose it as a way to replenish their energy mid-trip while also caring for their skin.

At Ueno Clinic, we tailor the approach to your individual symptoms and condition following a brief consultation with our physician.

May support: fatigue recovery, skin radiance, hormonal balance, menopausal concerns, general wellness.

Placenta therapy at Ueno Clinic Nagano
From ¥3,300 per session (tax incl.)

Full details (Japanese) →
05 HEALITE II LED THERAPY
05
HEALITE II LED Therapy
Zero Downtime Pain-Free Combinable with Other Treatments
HEALITE II LED Phototherapy

HEALITE II LED Phototherapy · Pain-free skin renewal

HEALITE II delivers specific wavelengths of LED light to support skin cell regeneration, anti-inflammation, and overall skin conditioning. Completely painless and non-invasive — simply relax while light does the work.

Ideal as a stand-alone treatment or combined after PicoSure or PRP to enhance results and support recovery. Suitable for sensitive skin, post-treatment care, dull complexion, or general skin conditioning during travel.

Healite II — Multi-area pricing (税込)
1 area (face / neck / back / arms / knees / calves / feet): ¥11,000
2 areas: ¥19,800 (+¥8,800) · 3 areas: ¥26,400 (+¥6,600)

Foot Massage (separate, non-LED)
Standalone ¥11,000 · Add-on with IV or Healite II ¥8,800

Combo with Glutathione IV: ¥25,300 · with Vitamin C IV: ¥22,000

Full details (Japanese) →
06 MEDICAL LASER HAIR REMOVAL
06
Medical Laser Hair Removal
3 Laser Devices Skin-Type Matched Ladies & Men’s
01 PRP Skin Regenerative Therapy
02 Stem Cell Culture Supernatant
03 PicoSure Laser
04 Placenta Injection
05 HEALITE II LED Therapy
06 Medical Laser Hair Removal

Ueno Clinic uses three laser devices — CLARITY II, GentleLase Pro, and Venus Velocity — selected according to your skin tone, hair type, and treatment area for a personalised approach.

Medical laser hair removal uses high-power devices unavailable at non-medical beauty salons, with physician oversight throughout.

Underarms (ladies): from ¥4,400 · Men’s underarms: from ¥5,500
VIO: from ¥5,500 · Full face: from ¥27,500
Men’s beard: from ¥11,000
6th session onwards: approx. 50% off

Full details (Japanese) →

Hours for International Guests

International guest appointments are available on Fridays and Saturdays. All visits are by appointment only — please contact us in advance via Email.

Frequently Asked Questions

Everything you need to know before your visit — answered in English.

🏥 Clinic & Booking
Does the physician speak English?
Yes. Our physician speaks English and will provide a full explanation of your treatment — including procedure details, expected results, risks, aftercare, and pricing — before we begin. You are welcome to ask any questions in English. Reception staff communicate primarily in Japanese, but the physician will be present for all consultations.
How do I book an appointment as an international visitor?
Please contact us via Email in advance. We do not accept English phone enquiries. Once we receive your message, we will reply in English to confirm availability, answer any questions, and prepare for your visit. We recommend contacting us at least 1 day before your preferred date.
Is there a consultation fee?
No consultation fee. We want your visit to be as accessible as possible, so there is no charge for the initial consultation.
What are the international guest hours?
Friday 9:00–20:00 and Saturday 9:00–15:00. All visits are by appointment only. Please note that phone enquiries in English are not available — Email only. We are happy to accommodate your sightseeing itinerary when scheduling.
What payment methods are accepted?
Cash and credit card (single payment only). Instalment payments and advance international bank transfers are not available.
How far is the clinic from Zenkoji Temple?
Approximately 5 minutes by taxi — fare is typically under ¥1,000. Free large parking is available on site for those travelling by car. From Nagano Station, the journey is also around 5 minutes by taxi.
Is there an acupuncture or osteopathy clinic for sore muscles and travel fatigue?
Yes — there is an acupuncture and osteopathy clinic within the same building. If you have tired shoulders, back pain, or general body fatigue from travel, please ask us. It is a wonderful complement to your beauty treatment visit.
Can I receive multiple treatments in one visit?
Yes, in many cases. For example, HEALITE can be combined with PicoSure or PRP on the same visit. Please let us know your interests when you enquire and we will suggest an efficient and safe combination tailored to your schedule.
✨ PRP Skin Regenerative Therapy
What exactly is PRP therapy?
PRP (Platelet-Rich Plasma) uses a small amount of your own blood, which is centrifuged to concentrate the platelet-rich layer, then injected back into your skin. The growth factors in the platelets stimulate your skin’s own regenerative processes — improving texture, firmness, and radiance from within.
Is PRP safe? Are there risks of allergic reactions?
Because PRP uses your own blood, the risk of allergic reaction or rejection is extremely low. Mild redness, swelling, or bruising at the injection site may occur and typically resolves within a few days. All risks will be explained clearly in English during your consultation.
Is there downtime after PRP?
There may be mild redness or slight swelling immediately after treatment, which usually subsides within 24–48 hours. Make-up can be applied the following day. We advise avoiding intense exercise, alcohol, and direct sun exposure for 24 hours. Most guests are able to continue their travel activities without significant disruption.
How many sessions are needed to see results?
Some improvement in skin quality may be noticed after a single session. Many international guests receive one session during their Japan visit and continue on a future trip — sometimes a year later. Results vary by individual, and our physician will give a personalised recommendation at your consultation.
Is Ueno Clinic a registered regenerative medicine facility?
Yes. Ueno Clinic is registered under Japan’s Act on the Safety of Regenerative Medicine — a requirement for any clinic offering PRP therapy in Japan, held by only a limited number of facilities nationwide. We have been offering PRP since 2007, with over 17 years of experience.
Can I receive PRP on my first visit?
Yes, but a physician consultation is required first to confirm suitability. Please allow extra time on your first visit. We strongly recommend contacting us in advance via Email so we can prepare your consultation efficiently.
🌿 Stem Cell Culture Supernatant
What is Umbilical Cord Stem Cell Culture Supernatant Therapy?
Ueno Clinic offers Human Umbilical Cord Stem Cell Culture Supernatant Therapy — therapy using the supernatant liquid produced when umbilical cord-derived stem cells are cultivated. The umbilical cord contains some of the youngest, most potent stem cells in the human body. During cultivation, these cells release hundreds of cytokines, growth factors, exosomes — including GDF-11, the “youth factor” researched at Harvard University and published in Science and Cell journals. When injected into the face, these bioactive substances stimulate your skin’s own regeneration and repair at a cellular level.
How is it different from PRP?
PRP uses concentrated growth factors from your own blood. Stem cell supernatant uses growth factors secreted by cultivated donor stem cells — providing a broader and more concentrated range of regenerative signals (500+ types vs. a more limited set in PRP). Both are powerful, and they can be combined for an enhanced effect. We recommend PRP as the first choice, with supernatant as the next step for those seeking deeper results.
Why does Ueno Clinic use Japanese-made domestic umbilical cord supernatant?
Ueno Clinic uses domestically manufactured supernatant sourced from Japanese donors at approved Japanese medical facilities. It passes rigorous safety screening including 5 virus tests (HBV, HCV, HIV, HTLV-1, B19V) and 4 bacterial tests. The product is stored at −80°C ultra-low temperature and used immediately after thawing — ensuring maximum potency and freshness. Umbilical cord-derived supernatant is rare: only a tiny fraction of available supernatant comes from umbilical cord origin, making it more potent and highly sought-after than alternatives.
Is there downtime after the injection?
There is minimal to no downtime. You may experience slight redness or swelling at the injection sites for a few hours, which typically resolves quickly. Make-up can be applied the following day. You can continue your travel and sightseeing activities normally.
What is the price?
The facial subcutaneous injection is ¥44,000 (tax incl.). Please contact us via Email for details and to check availability.
🔆 PicoSure Laser
What is PicoSure and how is it different from regular laser?
PicoSure is a picosecond laser that fires energy in trillionths of a second — far faster than conventional lasers. It uses pressure rather than heat to shatter pigment particles, resulting in less thermal damage to surrounding skin. It is effective across a wider range of concerns and suitable for all skin types, including Asian skin.
Is there downtime after PicoSure?
PicoSure is a low-downtime treatment. For spot treatments, you may experience mild redness for a few hours — no protective tape is required and make-up can be applied the same day. For full-face treatments, some temporary redness or slight darkening of treated spots may occur for a few days. Avoiding direct sun exposure for 1–2 weeks after treatment is important.
Can I go sightseeing after PicoSure?
For spot treatments, yes — you can typically continue your day normally. For full-face treatments, minimise sun exposure for the rest of the day and apply SPF50+ sunscreen. A visit to Zenkoji Temple or indoor sightseeing is generally fine.
How many sessions are needed?
For isolated age spots or freckles, visible improvement is often seen after just 1 session. For melasma, dullness, or pore concerns, 3–5 or more sessions are typically recommended — though results can be felt even after a single treatment. Your physician will assess your skin and give a personalised plan.
Is PicoSure available at other clinics in Nagano City?
The number of clinics offering PicoSure in Nagano City is very limited. Ueno Clinic has been equipped with PicoSure since 2017 and our physician has extensive hands-on experience with this device.
💉 Placenta Injection
What is placenta injection and why is it popular in Japan?
Placenta injection uses a pharmaceutical-grade extract from human placenta, rich in amino acids, growth factors, vitamins, and enzymes. It supports cellular metabolism, skin rejuvenation, hormonal balance, and fatigue recovery. It has been used in Japanese medical practice for decades with a well-established safety profile.
Is it good for travel fatigue recovery?
Absolutely. Many international visitors choose placenta injection specifically to restore energy mid-trip. The treatment takes only a few minutes, causes minimal discomfort, and requires no downtime — making it ideal to fit into a busy travel itinerary.
Are there any side effects?
Generally very well tolerated. Occasional mild redness or soreness at the injection site may occur and resolves quickly. You can continue normal activities immediately after treatment. Can be received by both men and women.
How quickly does it work and how long do effects last?
Some people notice increased energy or brighter skin within a few days of their first injection. The effects of a single session last approximately a few days to one week. For sustained results, ongoing sessions are recommended — many guests incorporate it into their Japan travel routine.
💡 HEALITE II LED Therapy
What is HEALITE II?
HEALITE II is a professional LED phototherapy device delivering specific wavelengths — 633nm (red light) for collagen stimulation and anti-ageing, and 830nm (near-infrared) for deep tissue healing and anti-inflammation. The treatment is completely painless and non-invasive.
Is there any downtime?
None at all. You can apply make-up and go sightseeing immediately after treatment. Many guests describe it as feeling like a warm, calming light — one of the most relaxing treatments we offer.
Who is HEALITE best suited for?
Anyone wanting to refresh and condition their skin without needles or downtime. Especially recommended for: post-travel skin dullness, sensitive or reactive skin, post-laser recovery (after PicoSure), and general skin hydration and anti-ageing support during your visit.
Can HEALITE be combined with other treatments?
Yes — HEALITE works exceptionally well after PicoSure or PRP therapy, soothing the skin and amplifying regenerative results. A typical combined visit might be: PicoSure or PRP → HEALITE. Sessions can usually be completed within a single appointment.
🌐 For International Visitors
🌏 International Guest Experience

“Ueno Clinic has had the privilege of welcoming guests from across Asia for aesthetic treatments.”

🇹🇼 Taiwan 🇨🇳 China 🇰🇷 Korea 🇹🇭 Thailand

Our physician speaks English and has experience treating international visitors. Every guest receives a complete explanation in English before treatment — including procedure details, expected outcomes, and aftercare.

Is it easy to communicate if I don’t speak Japanese?
Yes. Our physician speaks English and will handle all consultations, treatment explanations, and aftercare instructions in English. We have welcomed guests from Taiwan, China, Korea, and Thailand. Please contact us in advance via Email so we can prepare everything in English before your visit.
What should I prepare before my visit?
Please contact us via Email at least 1 day before your preferred date. Let us know which treatment(s) you are interested in and any relevant medical information (allergies, current medications, pregnancy). We will prepare your English consultation and ensure your visit runs smoothly from the moment you arrive.
I have allergies or am taking medication — is that okay?
Please inform us when you make your enquiry. Our physician will review your medical information during the consultation and confirm whether the planned treatment is suitable for you. Certain conditions may affect eligibility for specific treatments.
Can I visit on the same day as my Zenkoji visit?
Subject to availability, same-day visits may be possible. Email enquiries are the fastest way to check. From Zenkoji Temple, a taxi takes less than 5 minutes and costs under ¥1,000 — making it very easy to combine with your sightseeing.
Will everything be explained in English before treatment?
Yes, always. Our physician will explain the full procedure, expected outcome, risks, aftercare, and pricing in English before any treatment begins. We will not proceed until you are fully informed and comfortable. Your safety and understanding come first.

Location & Access

Ueno Clinic is perfectly positioned for visitors exploring Nagano’s iconic sights.

Zenkoji Temple Nagano
5 min by car
🛕 Zenkoji Temple
Snow Monkey Park Jigokudani Nagano
~40 min by car
🐒 Snow Monkey Park
Hakuba Valley Nagano Alps
~60 min by car
⛷ Hakuba Valley

Centrally located in Nagano City — within easy reach of the area’s major attractions.

  • 🛕 Zenkoji Temple5 min by car
  • 🚆 Nagano Station5 min by car
  • 🐒 Snow Monkey Park (Jigokudani)~40 min
  • ⛷ Hakuba Valley~60 min
  • ⛩ Togakushi Shrine~50 min
  • 🏯 Matsumoto Castle~50 min
Ueno Clinic building — Nagano City Miwa
Ueno Clinic
Ueno Clinic · Free Parking
4-6-2 Miwa, Nagano City

Clinic Information

Address4-6-2 Miwa, Nagano City
Nagano Prefecture 380-0803
ParkingFree · Large car park on site
TaxiFrom Zenkoji Temple: under ¥1,000
Approx. 5 min by taxi
Intl HoursFri 9:00–20:00 · Sat 9:00–15:00
📵 No English phone support
💬 Email only
BookingBy appointment only
Please contact at least 1 day ahead
Also in
Building
🏥 Acupuncture & Osteopathy Clinic
Tired shoulders · Back pain · Body fatigue
Same facility — ask us for a referral
✉️ Email
Booking
uenoiin.miwa.biyou@gmail.com
Reply within 24 hours

Trusted for 30 Years in Nagano

🏛

Est. Meiji 43

Over 30 years serving Nagano. A genuine local clinic — not a chain — with deep community roots.

🔬

Registered Regenerative Medicine

PRP conducted under Japan’s Act on the Safety of Regenerative Medicine. Government-registered facility since 2007.

Advanced Technology

PicoSure (US FDA cleared) — one of very few facilities offering this device in Nagano City. Three medical laser devices for hair removal.

🚗

Private & Accessible

Free large car park. Fully by appointment — discreet from arrival to departure.

💬

English Inquiries Welcome

Contact us via Email. We’ll help plan your treatment around your Nagano itinerary.

📍

Ideal Location

5 minutes from Zenkoji Temple and Nagano Station. Perfect for visitors to Hakuba, Snow Monkey Park, or Togakushi.

🌏

Visitors from Across Asia

Guests from Taiwan, China, Korea, and Thailand have visited Ueno Clinic. Our physician speaks English and every international visitor receives a full explanation before treatment begins.

Get in Touch

Please contact us before your visit · English welcome · Advance booking required

International Guest Hours
Friday: 9:00 – 20:00  |  Saturday: 9:00 – 15:00
By appointment only · Please book at least 1 day in advance

📵 Phone inquiries in English are not available.
✉️ Email / Booking: uenoiin.miwa.biyou@gmail.com
We will reply in English with a full explanation before your visit (within 24 hours).

4-6-2 Miwa, Nagano City · 5 min from Zenkoji Temple · Free parking
※ All treatments are performed by licensed physicians.
※ Results may vary by individual. Please consult our physician for details.

Official Website

日本語の公式サイトはこちら

For full treatment details in Japanese, please visit our official website.

🌐 日本語公式サイト  /  Official Japanese Website

ueno-iin-biyou-miwa.com

Thank You

Your reservation request has been submitted.
We will confirm your appointment within 24 hours by email.
填写完成,24小时内邮件确认。

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