PRP Therapy (Platelet-Rich Plasma) | English
No fillers. Nothing artificial.
Rejuvenate your skin with your own blood.
PRP Therapy (Platelet-Rich Plasma)
Regenerative skin treatment in Nagano, Japan
Worried that fillers might look unnatural, or heard stories about lumps after injections? At Ueno Clinic, we prepare pure, 100% additive-free PRP from your own blood — no growth-factor additives, no foreign substances. Your own platelets naturally improve wrinkles, under-eye circles, and sagging from within.
Why patients choose Ueno ClinicFree consultation · inquiries welcome · no pushy sales | Email & LINE in English, Japanese, or Chinese (phone: Japanese only) | English-speaking staff | Free parking
Wherever you are, it’s easy to start
Ueno Clinic sits near Zenkoji Temple in Nagano City — convenient for travelers, Nagano locals, and visitors from Tokyo alike.
Done in about 30 minutes, between sightseeing
We’re a 6-minute walk from Zenkojishita Station, close to Zenkoji Temple. The procedure takes about 30 minutes, and you can wear makeup just 10 minutes after — your snow-monkey, ski, or temple plans stay intact. Your skin begins to change 2–4 weeks later, after you’re back home — a gift from Japan to your future self.
Your local clinic for 30 years
A trusted neighborhood clinic serving Miwa, Nagano for 30 years — easy follow-up visits and long-term skin care. English-speaking staff are available, and you can message us on LINE anytime.
90 minutes by Shinkansen — an easy day trip
The Hokuriku Shinkansen takes you from Tokyo to Nagano in about 1.5 hours. Combine your visit with Zenkoji Temple and Shinshu cuisine, and turn skincare into a relaxed weekend escape from the city.
Grow better skin with your own blood — authentic regenerative medicine in Japan.
What is PRP therapy? (30-second summary)
PRP therapy extracts platelets — packed with natural growth factors — from your own blood and injects them into your skin. It stimulates collagen production to improve wrinkles, fine lines, under-eye circles, sagging, and overall skin quality from within. Unlike hyaluronic-acid fillers, PRP works through your own cells, so the change is gradual and natural — no one will guess you had anything done. Ueno Clinic uses pure 100% PRP with zero additives, injected across the entire face at one flat price.
- Price (tax incl.)
- ¥203,500 first visit
¥150,000 thereafter - First results
- From 2–4 weeks
Full effect in 3–6 months - Duration
- Years
Individual results vary - Downtime
- A few days
Makeup OK same day - Treatment area
- Full face
No per-area charges - Our approach
- Pure 100% PRP
Zero additives or growth-factor drugs
A facility registered under Japan’s Act on the Safety of Regenerative Medicine
In Japan, regenerative treatments such as PRP are strictly regulated by law. Ueno Clinic is officially registered under the Act on the Safety of Regenerative Medicine and provides treatment under government-defined safety standards — the assurance that makes medical care in Japan worth traveling for.
- Registered treatment: Cosmetic medicine using autologous platelet-rich plasma (PRP)
- Provision plan number: PC3150103
- Offered since: December 2007 (nearly two decades of PRP experience)
- Certified committee: Japan Anti-Aging Medical Association Certified Committee for Regenerative Medicine (no. NB3150019)
- Device approved under Japan’s Pharmaceuticals and Medical Devices Act: Mycells® PRP kit (approval no. 30400BZX00169000)
Concerns that PRP therapy addresses
- Wrinkles and fine lines (around the eyes, forehead, mouth)
- Sagging and deepening nasolabial folds
- Dark circles and crepey skin under the eyes
- Loss of firmness and elasticity
- Wanting an overall lift in skin quality
- Hesitant about hyaluronic acid or other foreign substances
- Wanting to look younger naturally — without anyone noticing
- Wanting results that last, not endless touch-ups
So that when you catch your reflection,
you still love the face looking back.
Our answer is PRP therapy — skin grown by your own blood.
Why we insist on “pure PRP”
Ueno Clinic’s PRP therapy uses only the platelets extracted from your own blood. Growth-factor drugs and other additives are never used.
Why are we so strict about this? Because we care less about a quick result than about how your skin looks ten years from now.
Some clinics add bFGF (basic fibroblast growth factor) or similar agents to boost the effect. However, it has been reported that additive-based methods may, in rare cases, cause lumps and other complications.
Because our PRP uses your blood and nothing else, those additive-related risks are avoided. The change is gradual — but genuine. Your own cells do the work, restoring your skin from within.
How PRP therapy works
PRP (Platelet-Rich Plasma) is a concentrate of the platelets in your blood. Platelets are rich in growth factors — the molecules your body uses to repair and regenerate damaged tissue.
PRP therapy applies this natural healing power to the skin. The injected growth factors activate fibroblasts, boosting production of collagen and elastin. Because regeneration unfolds gradually over 3–6 months, the change looks natural — friends may notice you look great without ever guessing why.
Key growth factors in platelets
Promotes cell proliferation, recruits fibroblasts, and stimulates new blood-vessel growth for better circulation.
Drives production of collagen and connective tissue, supporting firmness and elasticity.
Builds new blood vessels and improves circulation, delivering nutrients throughout the skin.
Support tissue repair and cell renewal, helping your skin regenerate itself.
Where we inject PRP
Rather than treating a single spot, we inject PRP across your entire face, tailored to your concerns — treating skin as a surface, not a point, for an overall improvement in quality.
No per-area charges. The whole face, one flat price. Injection sites and amounts are decided together with you during your consultation.
What to expect, and when
- Softening of wrinkles and fine lines
- Improvement in sagging and nasolabial folds
- Brighter under-eye area, less crepiness
- More firmness, elasticity, and glow
- Better skin texture overall
- Stimulated collagen production
(for travelers — after you’re home)
*Onset and duration of results vary between individuals.
Reference before & after examples
The photos below are quoted from official materials published by the manufacturer of the MyCells® kit we use. They are not cases from our clinic. Results vary between individuals and are not guaranteed.
Source: official materials of the MyCells® PRP harvesting kit manufacturer (MyCells LTD). The photos are quoted from manufacturer materials, not cases treated at our clinic. Results vary and are not guaranteed. | Treatment: injection of PRP prepared from the patient’s own blood into the face | Cost (tax incl.): ¥203,500 first session / ¥150,000 thereafter | Main risks & side effects: bruising, redness, swelling, pain, temporary lumps, infection, and others at the injection site.
Why international patients choose Ueno Clinic
Additive-free, pure 100% PRP
No bFGF or any other growth-factor drugs. From blood draw to injection, your platelets are simply concentrated — nothing added. That means no additive-related risks, ever.
Flat pricing, no hidden fees
One flat price for the entire face — never billed per area. Consultation, blood draw, anesthesia, and aftercare are all included. What you see is exactly what you pay.
30 years local, globally presented
Thirty years serving Nagano, PRP since 2007, and results presented at the International Society of Aesthetic Plastic Surgery (ISAPS). The director personally examines every patient, every visit.
Orthopedic, cosmetic, and dermatologic surgeon. For 30 years I have cared for the health and beauty of the Nagano community. We introduced PRP therapy in 2007 and have presented our work at ISAPS. I listen carefully to each patient’s skin concerns and goals, and propose only the treatment you can genuinely feel good about.
— This page is medically reviewed by Dr. Masaki Ueno.
Ueno Clinic’s PRP, by the numbers
As a facility registered under Japan’s Act on the Safety of Regenerative Medicine, we use the government-approved Mycells® PRP kit, and a physician examines you at every visit before treatment.
PRP therapy is a good fit if you…
A good fit
- Want to look younger naturally, without fillers or foreign substances
- Prefer lasting change over temporary fixes
- Worry about allergies and prefer a treatment made from your own blood
- Want to improve your whole face, not just one line
- Want subtle results no one will notice
- Want to experience Japan’s high standard of medical care during your trip
Please consult the doctor first
- Pregnant or breastfeeding
- Malignant tumor
- Blood-clotting disorder
- Active infection
How it works — from inquiry to follow-up back home
Contact us on LINE or by email (free)
Message us on LINE or email uenoiin.miwa.biyou@gmail.com with your concerns and preferred dates. Email and LINE are available in English, Japanese, and Chinese (phone is Japanese only). Planning around your travel itinerary? We’ll help you fit it in.
Visit & doctor’s consultation (initial fee ¥3,300)
The doctor examines your skin, discusses your goals, and explains the treatment, risks, and costs. Consultation-only visits are welcome — no obligation, no pushy sales. English-speaking staff are available.
Blood draw (a few minutes)
A small amount of blood is drawn from your arm — it takes just a few minutes.
Centrifugation — preparing your PRP
Your blood is spun in a dedicated centrifuge to concentrate the platelets. Nothing is added at any stage.
Full-face injection
The concentrated PRP is injected across the areas of concern. Numbing cream is available on request. Blood draw to injection takes about 30 minutes.
Aftercare — and follow-up after you’re home
We explain aftercare before you leave. Makeup is fine about 10 minutes after, so you can go straight back to sightseeing. Once home, reach us anytime on LINE or by email with questions.
Full face · first session
¥203,500(tax incl.)
Honestly? It isn’t cheap.
But it covers everything: pure additive-free 100% PRP, a device approved by Japanese regulators, full-face injection by the doctor — plus consultation, blood draw, anesthesia, and aftercare, all included. The price has its reasons.
Pricing
- Consultation & examination
- Blood draw & PRP preparation
- Anesthesia (numbing cream)
- Aftercare & follow-up visit
No fees beyond the listed price (tax included). Major credit cards accepted.
*For patients aged 60 and over, we recommend 3 or more sessions. All prices include tax.
The moment you start noticing — that’s the moment to start.
PRP relies on the power of your own platelets. Because your cells’ regenerative capacity gradually declines with age, the time you’re most likely to feel the difference is now — when you’ve just started to notice.
Begin with a free consultation and simply find out whether your skin is a good candidate.
Frequently asked questions
What is PRP therapy?
I don’t speak Japanese. Can I still visit?
I’m traveling in Japan on a tight schedule. Can it be done in one day?
How do I get there from Tokyo?
When will I see results?
How long do results last?
Is there downtime?
Does it hurt? Is anesthesia available?
What about allergies?
How is this different from PRP at other clinics?
Are there per-area charges? What’s included?
How can I pay?
Can I come just for a consultation? Will I be pressured?
How many sessions will I need?
Who cannot receive PRP?
What if I have questions after returning home?
About this treatment (uninsured, self-funded medicine)
- Self-funded treatment
- The PRP therapy described on this page is not covered by Japanese public health insurance and is provided as self-funded (private) treatment.
- Standard procedure
- Your blood is drawn and centrifuged to concentrate the platelets into PRP, which is then injected into areas of concern on the face. One session takes about 30 minutes from blood draw to injection.
- Cost (tax incl.)
- ¥203,500 first session / ¥150,000 from the second session. No costs beyond the listed prices.
- Main risks & side effects
- Bruising, redness, swelling, pain, itching, temporary lumps, or infection may occur at injection sites. Most resolve within days to about a week; consult the doctor if symptoms persist. Results vary between individuals.
- Regulatory status (regenerative medicine)
- This treatment is provided under a plan filed pursuant to Japan’s Act on the Safety of Regenerative Medicine (plan no. PC3150103; treatment name: cosmetic medicine using autologous platelet-rich plasma).
- Regulatory status (medical device)
- We use the Mycells® PRP kit, a highly controlled medical device approved under Japan’s Pharmaceuticals and Medical Devices Act (approval no. 30400BZX00169000; marketed by Veritas Corporation). This is a domestically approved device — not an unapproved one.
- Contact
- Ueno Clinic (Medical Corporation Ichijukai) — LINE (https://lin.ee/PfLLLef) or email uenoiin.miwa.biyou@gmail.com. Questions about this page are always welcome.
Location & hours
Ueno Clinic (Medical Corporation Ichijukai)
- Departments
- Cosmetic surgery & dermatology (orthopedics on site)
- Address
- 4-6-2 Miwa, Nagano City, Nagano 380-0803, Japan
- Getting here
- 6-min walk from Zenkojishita Station (Nagano Electric Railway) / Free parking
From Tokyo: Hokuriku Shinkansen to Nagano Station (approx. 1.5 h), then a 10-min taxi or 5-min local train to Zenkojishita
Sightseeing: within walking distance of Zenkoji Temple - Inquiries & booking (English · Japanese · Chinese)
- LINE: lin.ee/PfLLLef
Email: uenoiin.miwa.biyou@gmail.com - Phone
- +81-26-235-3514 (cosmetic booking line)
*Phone support is available in Japanese only. For English or Chinese, please use LINE or email.
Hours
| Mon | Tue | Wed | Thu | Fri | Sat | Sun | |
|---|---|---|---|---|---|---|---|
| AM 9:00–12:00 | ○ | ○ | ○ | ○ | ○ | ○ | × |
| PM | 14:00 –17:00 | 14:00 –17:00 | × | 14:00 –17:00 | 14:00 –20:00 | 13:00 –15:00 | × |
Last reception is 30 minutes before closing (11:30 for morning hours).
*Friday afternoons until 20:00; Saturday afternoons 13:00–15:00.
We welcome: patients from across Nagano Prefecture, and international visitors and residents traveling from Tokyo, Hakuba, Karuizawa, and beyond. Planning a visit around your Japan itinerary? Message us on LINE or by email and we’ll help.
Start with a free consultation — in English
“I just want to know if it would suit me” is a perfectly good reason to write.
No need to decide on a ¥200,000 treatment today — let’s simply talk first.
- LINE & email consultations are free
- Questions-only welcome
- No pushy sales
- In English · Japanese · Chinese
In-person consultation: ¥3,300 initial fee (tax incl.), with no obligation to proceed.
6-min walk from Zenkojishita Station / free parking. *Fees may vary with treatment details and volume.
This page is medically reviewed by Dr. Masaki Ueno, Director of Ueno Clinic (Medical Corporation Ichijukai). | Last updated: July 2026