Ten minutes to a softer,
younger-looking expression.
Botulinum Toxin (Botox-type) Injections in Nagano, Japan
Wrinkle smoothing · jaw slimming · bruxism · sweat reduction
Forehead lines, frown lines, crow’s feet, a square jaw from strong masseter muscles, nighttime teeth grinding, underarm sweat — all treatable with a quick botulinum toxin injection. At Ueno Clinic the doctor personally examines you and performs every injection, starting with a conservative dose for first-timers so your face never looks frozen. The procedure takes about 10 minutes, and makeup is fine right after.
Free consultation · questions welcome · no pushy sales | LINE & email in English, Japanese, or Chinese (phone: Japanese only) | English-speaking staff | Free parking
A ten-minute treatment that fits any schedule
Ueno Clinic sits near Zenkoji Temple in Nagano City. With almost no downtime, botulinum toxin injections fit easily into a trip, a workday, or a weekend.
Done between sightseeing stops
We’re a 6-minute walk from Zenkojishita Station, close to Zenkoji Temple. The injection takes about 10 minutes and makeup is fine immediately after — snow monkeys, ski slopes, and temples all stay on today’s itinerary. Effects appear 2–3 days later, right around the time you head home.
Your local clinic for regular upkeep
Effects last about 3–4 months, so regular maintenance keeps results steady. A clinic rooted in Nagano for 30 years makes follow-ups easy — and Fridays & Saturdays are discount days.
90 minutes by Shinkansen
The Hokuriku Shinkansen brings you from Tokyo to Nagano in about 1.5 hours — an easy day trip. Friday evening hours run until 8:00 PM, so even an after-work visit is possible. Transparent flat pricing, no upselling.
What are botulinum toxin injections? (30-second summary)
Botulinum toxin (type A — commonly known as Botox) temporarily relaxes overactive muscles. It softens expression lines on the forehead, between the brows, and around the eyes, slims a square jaw by shrinking the masseter muscles, eases teeth grinding and clenching, and reduces underarm sweating. Ueno Clinic uses Neuronox — derived from the same bacterial strain as Allergan’s Botox, converted 1:1 unit-for-unit — with every injection planned and performed by the doctor. Effects begin in 2–3 days and last about 3–4 months for expression lines.
- Price (tax incl.)
- ¥17,600 per area
¥11,000 on Fri & Sat - Procedure time
- About 10 min
incl. prep & marking - Effects appear
- In 2–3 days
peak at ~1 month - Duration
- 3–4 months
jaw 4–6 mo · sweat 3–8 mo - Downtime
- Almost none
makeup right after - Product
- Neuronox
MFDS-approved (Korea) — see notes below
Concerns that botulinum toxin addresses
- Horizontal lines when you raise your eyebrows
- “Angry-looking” vertical lines between the brows
- Crow’s feet that show whenever you smile
- A square jawline from strong masseter muscles
- Teeth grinding at night, jaw clenching by day
- A dimpled, “orange-peel” chin
- Underarm sweat that limits what you wear
- Wanting subtle results no one will notice
Expression lines etch deeper with every year —
the earlier you relax them, the less they set in.
How it works
Expression lines are creases folded into the skin by repeated muscle contraction. Injected into the target muscle, botulinum toxin temporarily blocks the nerve signal that tells the muscle to contract. The overworked muscle relaxes — lines soften, an enlarged masseter gradually slims, and sweat-gland signals quiet down.
The effect is reversible: over several months the nerve endings regenerate and the effect fades naturally. Nothing permanent is changed — one reason this is among the most widely performed cosmetic treatments in the world.
We use Neuronox (Medytox, Korea), produced from the same Type A Hall strain as Allergan’s Botox with a 1:1 unit conversion — comparable effect and duration at a more reasonable price.
Areas we treat
The doctor tailors injection points and dose to your expression habits and muscle strength.
Horizontal lines
Frown lines between brows
Smile lines around the eyes
Bunny lines
Dimpled “orange-peel” texture
Slimming · bruxism · clenching
Neck bands · jawline (Nefertiti)
Excessive sweating
*First-time patients receive a deliberately conservative dose to keep expressions natural. A touch-up can be added at a follow-up visit if you want a stronger effect.
When effects appear, and how long they last
(treated mid-trip, you’ll see results around the flight home)
Jaw slimming 4–6 mo · sweating 3–8 mo
*Onset and duration vary between individuals. Regular sessions keep results stable; the masseter shrinks progressively with repeat treatments, allowing longer intervals.
Pricing
| 1 area | ¥17,600¥11,000 |
| 2 areas | ¥35,200¥22,000 |
| 3 areas | ¥52,800¥33,000 |
How it works — about 30 minutes at the clinic
Contact us on LINE or by email (free)
Message us on LINE or email uenoiin.miwa.biyou@gmail.com with the areas you’re considering and your preferred dates. LINE and email are available in English, Japanese, and Chinese (phone is Japanese only).
Visit & doctor’s consultation (initial fee ¥3,300)
The doctor reviews your expression habits and muscle strength, then explains dose, expected results, and risks. Consultation-only visits are welcome — no obligation, no pushy sales.
Injection (about 10 minutes)
After disinfection and marking, injections are made with an ultra-fine needle. Most patients describe it as easier than expected.
Straight back to your day
Makeup is fine immediately. For the rest of the day, avoid rubbing the injected areas, strenuous exercise, alcohol, and long hot baths or onsen. Effects begin in 2–3 days.
Follow-up — even after you’re home
Reach us anytime on LINE or by email. Want a stronger effect? A touch-up (¥12,100) can be added at a follow-up visit.
Frequently asked questions
Will my face look frozen or unnatural?
I don’t speak Japanese. Can I still visit?
I’m traveling on a tight schedule. Can it be done in one day?
Does it hurt?
When will I see results, and how long do they last?
How many sessions does jaw slimming take?
Is there downtime?
What product do you use? Is it safe?
Who should not receive botulinum toxin?
What’s included in the price? How can I pay?
What is the Friday & Saturday special?
What if I have questions after returning home?
Important notes on this treatment (self-funded medicine)
- Self-funded treatment
- The botulinum toxin injections described on this page are not covered by Japanese public health insurance and are provided as self-funded (private) treatment.
- Standard procedure
- A type-A botulinum toxin preparation is injected into target muscles (expression muscles, masseter, etc.) or intradermally (for hyperhidrosis). One session takes about 10 minutes.
- Cost (tax incl.)
- Expression lines: 1 area ¥17,600 / 2 areas ¥35,200 / 3 areas ¥52,800. Both masseters ¥52,800. Both underarms ¥66,000. Touch-up ¥12,100. Friday & Saturday special: 1 area ¥11,000 / 2 areas ¥22,000 / 3 areas ¥33,000. Initial consultation fee ¥3,300 applies separately.
- Main risks & side effects
- Bruising, swelling, redness, or pain at injection sites; headache; a feeling of stiffness in expressions; slight asymmetry of the smile. Most resolve within days to a few weeks. Effects vary between individuals and are temporary and reversible.
- About the unapproved medicine used
- Neuronox (Medytox Inc., Korea) is approved by Korea’s Ministry of Food and Drug Safety (MFDS) but has not been approved under Japan’s Pharmaceuticals and Medical Devices Act. It is imported by the attending physician through regular channels in the manufacturing country. A domestically approved product of the same class exists in Japan (Allergan’s Botox Vista). Japan’s relief system for adverse drug reactions does not apply to unapproved medicines. The doctor explains this fully at the consultation and proceeds only with your consent.
- Who cannot receive this treatment
- Patients who are pregnant or breastfeeding, have neuromuscular disorders such as myasthenia gravis, or have an infection at the injection site. Confirmed by the doctor at consultation.
- Contact
- Ueno Clinic (Medical Corporation Ichijukai) — LINE (https://lin.ee/PfLLLef) or email uenoiin.miwa.biyou@gmail.com. Questions about this page are always welcome.
Location & hours
Ueno Clinic (Medical Corporation Ichijukai)
- Departments
- Cosmetic surgery & dermatology (orthopedics on site)
- Address
- 4-6-2 Miwa, Nagano City, Nagano 380-0803, Japan
- Getting here
- 6-min walk from Zenkojishita Station (Nagano Electric Railway) / Free parking
From Tokyo: Hokuriku Shinkansen to Nagano Station (approx. 1.5 h), then a 10-min taxi
Sightseeing: within walking distance of Zenkoji Temple - Inquiries & booking (English · Japanese · Chinese)
- LINE: lin.ee/PfLLLef
Email: uenoiin.miwa.biyou@gmail.com - Phone
- +81-26-235-3514 (cosmetic booking line)
*Phone support in Japanese only. For English or Chinese, please use LINE or email.
Hours
| Mon | Tue | Wed | Thu | Fri | Sat | Sun | |
|---|---|---|---|---|---|---|---|
| AM 9:00–12:00 | ○ | ○ | ○ | ○ | ○ | ○ | × |
| PM | 14:00 –17:00 | 14:00 –17:00 | × | 14:00 –17:00 | 14:00 –20:00 | 13:00 –15:00 | × |
Last reception 30 minutes before closing (11:30 for mornings).
*Friday afternoons until 20:00; Saturday afternoons 13:00–15:00.
Fridays & Saturdays are botulinum-toxin discount days.
Start with a free consultation — in English
“Can this area be treated?” “Roughly how much would it cost?”
Questions alone are always welcome. It starts with one LINE message.
- LINE & email consultations are free
- Questions-only welcome
- No pushy sales
- In English · Japanese · Chinese
In-person consultation: ¥3,300 initial fee (tax incl.), with no obligation to proceed.
6-min walk from Zenkojishita Station / free parking.
This page is medically reviewed by Dr. Masaki Ueno, Director of Ueno Clinic (Medical Corporation Ichijukai). | Last updated: July 2026